Thyroid hormone deficiency and coronary artery disease

  • Saira Shan Government Lady Attichison Hospital, Lahore, (Pakistan)
  • Shumaila Aslam Government Lady Attichison Hospital, Lahore, (Pakistan
  • Nazish Saleem Institute of Chemistry, New Campus, University of the Punjab, Lahore, (Pakistan)
  • Nayab Batool Rizvi Institute of Chemistry, New Campus, University of the Punjab, Lahore, (Pakistan)
Keywords: Thyroid hormone, Hypothyroidism, Coronary artery disease, Thyroid stimulating hormone, Hyperhomocysteinemia

Abstract

Saira Shan, B.Sc, MBBS1, Shumaila Aslam, MBBS2,
Nazish Saleem, BS (Hons), M.Phil, BS. Ed3,
Nayab Batool Rizvi, M.Sc, PhD4, Shan Elahi, M.Sc, PhD5

1House Officer; 2Woman Medical Officer
Government Lady Aitchison Hospital, Lahore, (Pakistan)
3Lecturer; 4Assistant Professor
Institute of Chemistry, New Campus, University of the Punjab, Lahore, (Pakistan)
5Principal Scientist, Centre for Nuclear Medicine (CENUM), Mayo Hospital, Lahore, (Pakistan)

Correspondence: Dr. Shan ElahiCentre for Nuclear Medicine (CENUM), PO Box No.53, Mayo Hospital, Lahore, (Pakistan); Phone: 092-42-9214436-38 E-mail: shan.elahi@gmail.com

SUMMARY

The heart is sensitive to thyroid hormone action and thyroid dysfunctions. Thyroid hormone deficiency (hypothyroidism) either overt or subclinical has adverse cardiovascular consequences. They results from direct influences of hypothyroidism on heart function as well as due to secondary effects like atherogenic lipid profile, diastolic hypertension and impaired endothelial function leading to atherosclerosis. This review summarizes the basic and clinical studies on the role of hypothyroidism in development of atherosclerosis and traditional risk factors for coronary artery disease.

Published
01-19-2019
How to Cite
Shan, S., Aslam, S., Saleem, N., & Rizvi, N. B. (2019). Thyroid hormone deficiency and coronary artery disease. Anaesthesia, Pain & Intensive Care, 21(4), 489-496. Retrieved from https://apicareonline.com/index.php/APIC/article/view/94
Section
Review Article