Malignant hyperthermia

Abstract

Malignant hyperthermia is a hypermetabolic syndrome triggered in susceptible individuals by potent inhalation agents, succinylcholine, vigorous exercise and heat. Hyperthermia may or may not be accompanied by muscle rigidity. Aggressive management, including peripheral and core cooling techniques, oxygenation, hyperventilation, hydration and control of acidosis need to be promptly initiated with dantrolene infusion