The effect of dopamine pre-treatment on intubating conditions and haemodynamics during rapid tracheal intubation using propofol and rocuronium

  • Sandip Sinha Department of Anaesthesiology, Institute of Post Graduate Medical Education and Research (IPGMER), 244, Acharya Jagadish Chandra Bose Road, Kolkata-700020.
  • Manjushree Ray Department of Anaesthesiology, Institute of Post Graduate Medical Education and Research (IPGMER), 244, Acharya Jagadish Chandra Bose Road, Kolkata
  • Maitreyee Mukherjee Department of Anaesthesiology, Institute of Post Graduate Medical Education and Research (IPGMER), 244, Acharya Jagadish Chandra Bose Road, Kolkata
  • Sajib Chatterjee Department of General Surgery, NRSMCH, West Bengal (India)
  • Avijit Hazra Department of Anaesthesiology, Institute of Post Graduate Medical Education and Research (IPGMER), 244, Acharya Jagadish Chandra Bose Road, Kolkata
  • Nabanita Das Department of Anaesthesiology, Institute of Post Graduate Medical Education and Research (IPGMER), 244, Acharya Jagadish Chandra Bose Road, Kolkata
Keywords: Rapid sequence induction, dopamine pre-treatment, rocuronium, propofol

Abstract

Aims and Objectives: To assess intubating conditions and haemodynamic changes in patients pre-treated with dopamine during rapid tracheal intubation using rocuronium and propofol.

Methodology: Forty adult patients of ASA I and II, aged 20–60 years, scheduled for elective as well as emergency surgery, were included in this prospective randomized open label group double blind study. In Group A patients injection dopamine infusion 3 μg/Kg/min and in Group B patients an equal volume of normal saline was infused over 15 minutes before administering  general anesthesia using propofol 2 mg/Kg and rocuronium 0.6 mg/Kg .  Laryngoscopy and tracheal intubation was attempted at 60 seconds, whereby anaesthesiologist assessed the intubating conditions.

Duration of laryngoscopy , Train of four ratio (TOF ratio) at 60 sec after rocuronium administration, time from disappearance of all four twitches on TOF count,  intubation score at 60 seconds were recorded. Mean arterial pressure, pulse rate and oxygen saturation were recorded at different time points.

Published
02-03-2019
How to Cite
Sinha, S., Ray, M., Mukherjee, M., Chatterjee, S., Hazra, A., & Das, N. (2019). The effect of dopamine pre-treatment on intubating conditions and haemodynamics during rapid tracheal intubation using propofol and rocuronium. Anaesthesia, Pain & Intensive Care, 152-156. Retrieved from https://apicareonline.com/index.php/APIC/article/view/508
Section
Original Articles