The effects of 7 mg levobupivacaine on maternal hemodynamics with side effects in combined spinalepidural anaesthesia for cesarean section

  • Handan Gulec Training Hospital, Anaesthesia and Reanimation Clinic, Ankara (Turkey)
  • Semih Degerli Training Hospital, Anaesthesia and Reanimation Clinic, Ankara (Turkey)
  • Esra Ozayar Training Hospital, Anaesthesia and Reanimation Clinic, Ankara (Turkey)
  • Fatma Bercin Training Hospital, Anaesthesia and Reanimation Clinic, Ankara (Turkey)
  • Saziye Sahin Gazi University Faculty of Dentistry Anesthesiology Reanimation Department Ankara (Turkey)
Keywords: Cesarean section, Combined spinal-epidural, Spinal anesthesia, Hemodynamics, Hypotension, Levobupivacaine

Abstract

Background: It has been reported that 10-15 mg local anaesthetic is enough for cesarean sections. Reduced doses of levobupivacaine may decrease the incidence of associated complications e.g. hypotension, nausea, vomiting and the vasopressor use. The primary objective of this study was to compare 7 mg and 10 mg doses of intratheca levobupivacaine on maternal hemodynamics. The secondary objective was to determine the differences in sensory block, the vasopressor use, associated side effects and a need for additional analgesics between the groups.Methodology: Following ethical committee approval, thirty three women presenting for elective cesarean delivery were randomly assigned to one of the 2 groups. Group-7 received 7 mg intrathecal levobupivacaine and Group-10 received 10 mg. Women in both groups received 10 ml/kg crystalloids intravenously, at the time of initiation of combined spinal – epidural anesthesia. Surgery began when a sensory level was at T4. Maternal hemodynamics and sensorimotor levels were recorded at regular intervals. Side effects, additional analgesics and the vasopressor use were documented.Results: No difference was observed in the incidence of hypotension ( p:0.482), bradycardia (p:1.00) or nausea and vomiting (p:0.448) between two groups. Incidence of additional analgesic requirement and vasopressorrequirement was also similar in both groups (p:0.383). Conclusion: Intrathecal levobupivacaine 10 mg and 7 mg yielded similar maternal hemodynamics, sensory block, side effects and additional analgesic requirement during cesarean delivery.

Published
02-03-2019
How to Cite
Gulec, H., Degerli, S., Ozayar, E., Bercin, F., & Sahin, S. (2019). The effects of 7 mg levobupivacaine on maternal hemodynamics with side effects in combined spinalepidural anaesthesia for cesarean section. Anaesthesia, Pain & Intensive Care, 127-130. Retrieved from https://apicareonline.com/index.php/APIC/article/view/505
Section
Original Articles