Gilbert’s syndrome

  • Alka Chandra Senior Specialist Hindurao Hospital & Head of Dept, RBIPMT, New Delhi (India)
  • Jayant Nagesh Banavaliker Department of Chest & T.B, RBIPMT, New Delhi (India)
  • R Madhubala Dixit Department of Anaeshtesiology, Hindurao Hospital, New Delhi (India)
Keywords: Gilbert’s syndrome, Glucuronyl transferase, TENS

Abstract

Gilbert’s syndrome is a form of hereditary non-hemolytic jaundice transmitted by autosomal dominant pattern.Since there is low glucuronyl transferase activity in the liver there is a risk for anesthetic toxicity with a possibility of a catastrophic outcome. It is important for the anesthesiologists to understand the pathophysiology of the disease and the conditions leading to decreased glucuronyl transferase activity. We report a case of Gilbert’s syndrome with hypertension, operated for cholelithiasis under thoracic epidural analgesia supplemented with transcutaneous electrical nerve stimulation in the postoperative period. Minimal administration of intravenousdrugs, maintaining the organ perfusion and postoperative pain relief using epidural anesthesia offers a safe conduct of anesthesia which can be considered as an alternative to general anesthesia.

Published
02-03-2019
How to Cite
Chandra, A., Banavaliker, J. N., & Dixit, R. M. (2019). Gilbert’s syndrome. Anaesthesia, Pain & Intensive Care, 195-197. Retrieved from https://apicareonline.com/index.php/APIC/article/view/498
Section
Case Reports