Dexmedetomidine as an adjuvant to hyperbaric spinal bupivacaine for infra-umbilical procedures: A dose related study

Abstract

Aims & Objectives: Various adjuncts have been used with local anesthetics in spinal anesthesia to provide good quality of intra-operative and better post-operative analgesia. Dexmedetomidine is a new α-2 adrenergic agonist, now being used as a neuraxial adjuvant.

The aim of our study was to investigate the effect of intrathecal administration of dexmedetomidine 5 µg and 10 µg, as an adjuvant to bupivacaine 0.5%, on the onset and duration of sensory and motor block, the hemodynamic effects, the duration of analgesia and the occurrence of side effects.