Sustained low-efficiency dialysis and intravenous immunoglobulin in geriatric expanded dengue syndrome: A case study

Abstract

Expanded Dengue Syndrome (EDS) can cause severe multi-organ involvement, especially in geriatric patients. This report details a 91-year-old woman whose dengue fever progressed to shock and EDS, affecting multiple organs. Hemodynamic instability prompted Sustained Low-Efficiency Dialysis (SLED) for Acute Kidney Injury (AKI), which provided renal support without further compromise. Intravenous Immunoglobulin (IVIG) was also administered. The patient improved, with stabilized hemodynamics and resolved organ dysfunction, leading to discharge without sequelae. This case report is of utmost importance as it highlights the potential utility of SLED and IVIG in managing complex EDS in geriatric patients. However, further research is needed to establish standardized protocols for management of EDS.

Abbreviations: AKI: Acute Kidney Injury, EDS: Expanded Dengue Syndrome, IVIG: Intravenous Immunoglobulin, SLED: Sustained Low-Efficiency Dialysis

Keywords: Expanded dengue syndrome; Geriatric; Sustained low-efficiency dialysis; Intravenous immunoglobulin; Multi-organ involvement

Citation: Putra ES, Khaerunnissya RL. Sustained low-efficiency dialysis and intravenous immunoglobulin in geriatric expanded dengue syndrome: A case study. Anaesth. pain intensive care 2025;29(8):1032-1036. DOI: 10.35975/apic.v29i8.3035

Received: May 17, 2025; Revised: August 26, 2025; Accepted: September 04, 2025