A comparison between intrathecal isobaric levobupivacaine 0.5% and isobaric ropivacaine 0.5% in lower limb surgeries: a prospective, randomized, double blind study
Abstract
Background & Objectives: Levobupivacaine and ropivacaine are the two recently introduced local anesthetics alternatives to bupivacaine in clinical practice. The present study has been conducted to compare the efficacy of intrathecal isobaric levobupivacaine 0.5% and isobaric ropivacaine 0.5% in terms of sensory and motor blockade characteristics, intraoperative hemodynamics stability and side effects if any.
Methodology: A prospective randomized double blind study was conducted in 60 ASA grade I-II patients in age groups of 18-60 years undergoing lower limb surgeries. Patients were divided in 2 groups of 30 patients each. Group L received 3 ml isobaric levobupivacaine 0.5%, whereas patients in Group R received 3 ml isobaric ropivacaine intrathecally. Patients were assessed for onset and duration of sensory and motor blockade, intraoperative hemodynamic parameters and side effects.