Disulfiram induced bilateral foot drop; an under-recognised cause for peripheral neuropathy

  • Salman Mansoor Department of Neurology, Sligo University Hospital, Sligo (Ireland)
  • Kevin Murphy Department of Neurology, Sligo University Hospital, Sligo (Ireland)
  • Siobhan Kelly Department of Neurology, Sligo University Hospital, Sligo (Ireland)
Keywords: Disulfiram, Foot drop, Peripheral neuropathy, Chronic alcoholism

Abstract

Disulfiram is commonly used in chronic alcoholics as an effective treatment. We report a case of a 50 years old Irishman who was on disulfiram for the last nine years. He developed progressive bilateral foot drop, which started with one foot and later on progressed to bilateral involvement over a period of eight months. Our case report highlights the need to take into consideration disulfiram as one of the possible causes of peripheral neuropathy, which is a rare side effect of this drug.

Abbreviations: Abductor Digiti Minimi – ADM; Extensor Digitorum Brevis – EDB, Abductor Hallucis – AH; Antinuclear antibodies - ANA; Ribonucleoprotein – RNP; Cerebrospinal fluid – CSF; Non-recordable – NR; Electromyography – EMG; Flexor digitorum indicis – FDI; Sensory nerve action potential - SNAP

Citation: Mansoor S, Murphy K, Kelly S. Disulfiram induced bilateral foot drop; an under-recognised cause for peripheral neuropathy. Anaesth pain intensive care 2020;24(1):__

DOI: https://doi.org/10.35975/apic.v24i1.

Received – 28 December 2019;

Reviewed – 10 January 2020;

Accepted - 10 January 2020;

Published
05-07-2020
How to Cite
Mansoor, S., Murphy, K., & Kelly, S. (2020). Disulfiram induced bilateral foot drop; an under-recognised cause for peripheral neuropathy. Anaesthesia, Pain & Intensive Care, 24(1), 108-110. https://doi.org/10.35975/apic.v24i1.1234