Analgesic effects of dexmedetomidine with hyperbaric bupivacaine in spinal anesthesia for patients undergoing Illiazorov surgery

Abstract

Objective: To examine the efficacy of dexmedetomidine with hyperbaric bupivacaine 0.5% in spinal anesthesia for patients undergoing Illiazorov surgery.
Methodology: This cross-sectional/observational study was conducted at Orthopedics and Spine Centre, Ghurki Trust Teaching Hospital (GTTH) Lahore for two months from 20th August 2018 to 20th October 2018. In this study 52 patients of both genders undergoing lower limb surgeries were included. Patient’s ages ranged from 18 to 65 y. Detailed medical history and informed consent was taken from all of the patients. The patients were randomly divided into two groups using a computer generated random number table. Group-I  included 26 patients and received inj. dexmedetomidine 10 µg in 0.5 ml of normal saline along with 12.5 mg of 0.5% hyperbaric bupivacaine (2.5 ml) , while the Group-II had 26 patients and received only 0.5ml  of  normal saline with 12.5 mg of 0.5% hyperbaric bupivacaine(2.5ml). Results were noted in both groups as time to achieve T10 sensory blockade and time to first rescue analgesia after spinal anesthesia.
Results: There were 19 (73.08%) male patients and 7 (26.92%) females in Group-I while in Group-II 21 (80.77%) patients were male and 5 (19.23%) were females. We observed the results were similar with respect to the time to reach T10 sensory blockade. But, we observed a significant difference in time to first rescue analgesia after spinal anesthesia. In Group-I, it was 270.35 min while in Group-II, it was 182.25 min.
Conclusion: In this study, we concluded that there was a significant difference in two groups with respect to the time to first rescue analgesia after spinal anesthesia with and without using dexmedetomidine in addition to 0.5% bupivacaine in spinal anesthesia for Illiazorov surgery.
Citation: Rehman AU, Siddiq S, Qadeer K, Nawaz A, Hussain K, Ashfaq N, Aziz L. Analgesic effects of dexmedetomidine with hyperbaric bupivacaine in spinal anesthesia for patients undergoing Illiazorov surgery. Anaesth. pain & intensive care 2019;23(1)___
Received – 11 November 2018; Reviewed – 17, 19, 20 November 2018; Corrected – 10 April 2019; Accepted - 10 April 2019